Cleanroom Design & Construction
Bespoke cleanroom solutions engineered to meet the most demanding regulatory and operational requirements.
Cleanroom design, engineering and compliant cleanroom construction.
Bespoke Cleanrooms
Total Clean Air is a leading specialist in cleanroom design, engineering and compliant cleanroom construction for organisations that require controlled environments built to the highest standards. From pharmaceutical and biotech facilities to semiconductor, aerospace, defence and advanced manufacturing applications, we design and deliver cleanrooms that are fully aligned with ISO 14644, EU GMP Annex 1, MHRA, and FDA expectations.
Our cleanrooms are engineered for long-term performance, energy efficiency and operational reliability. Whether you require a new facility, a cleanroom extension, or the redesign of an existing space, we provide a complete, turnkey service that guides you from concept to full validation.
Complete Cleanroom Design Services
Our team creates cleanrooms that are tailored to your exact needs, combining contamination-control expertise with practical engineering experience. The design process covers every stage necessary to create a compliant, high-functioning controlled environment.
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Compliance-Led Design – Custom cleanroom layouts meeting ISO 14644 and GMP standards.
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Airflow & Filtration – HEPA/ULPA systems with precise pressure and temperature control.
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Integrated Engineering – Fully coordinated MEP, process, and monitoring systems.
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Modular & Containment – Scalable modular cleanrooms and CL2/CL3 laboratories.
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Validation Support – Audit-ready documentation and lifecycle support.
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Total Clean Air offers a complete turnkey package for all your cleanroom requirements
Why choose Total Clean Air?
Proven Expertise & Accredited Assurance
Choosing the right cleanroom designer has a direct impact on performance, compliance, and long-term operating costs. Total Clean Air brings proven expertise across highly regulated industries, including pharmaceuticals, biotechnology, aerospace, micro-electronics, medical device manufacturing, and R&D. As a UKAS ISO 17025-accredited organisation, we apply scientifically robust, independently verified methodologies throughout the design and installation process, giving you confidence in audit readiness and regulatory compliance.
Why choose Total Clean Air?
Turnkey Delivery & Engineering Excellence
With Total Clean Air, there is no need to manage multiple contractors. We provide a fully integrated, turnkey service covering cleanroom design, engineering, construction, controls, containment, and validation. This single-point responsibility ensures consistent quality, reduced project risk, and seamless coordination from concept through to completion. Our cleanrooms are also engineered with energy efficiency in mind, helping reduce operational costs without compromising performance.
Why choose Total Clean Air?
Long-Term Partnership & Lifecycle Support
Our commitment doesn’t end at handover. Through our ‘We Care’ promise, we support your cleanroom throughout its operational life, offering ongoing maintenance, testing, re-certification, and performance optimisation. This long-term partnership approach ensures sustained compliance, reliability, and value well beyond initial installation.