Healthcare Laboratories

Total Clean Air supports healthcare organisations across a broad range of clinical and laboratory environments. Our cleanroom solutions are applied throughout the healthcare sector:

In Hospital Pharmacy and Aseptic Units, we deliver ISO Class 5 cleanrooms for sterile preparation of intravenous drugs, TPN, and cytotoxics, designed to meet MHRA, HTM 01-01, and EU GMP standards while supporting future expansion.

For Operating Theatres, we design ultra-clean air (UCA) environments that minimise infection risk during surgical procedures, in line with HTM 03-01 and relevant British Standards.

Our Sterile Services solutions support compliant decontamination, sterilisation, and storage of medical instruments, ensuring they are returned to use in a verified sterile condition.

We also create controlled environments for Microbiology and Pathology Laboratories, including containment facilities with appropriate biosafety levels for diagnostic and research work.

In Medical Device Manufacturing, our ISO-classified cleanrooms support compliance with UK regulations and ISO 13485 for production and testing.

For advanced therapies, we deliver Cell and Gene Therapy Facilities with Grade A/B environments for ATMP manufacture, aligned with EU GMP Annex 1 and MHRA guidance.

Additionally, our Research and Clinical Trial Laboratories provide modular cleanroom solutions for investigational medicinal products and compliant clinical research.

Additionally, we offer Research and Clinical Trial Laboratories with modular, scalable cleanroom solutions that enable the compliant manufacture of investigational medicinal products and support clinical research activities.

Continuous environmental monitoring is a regulatory requirement for the majority of healthcare cleanroom applications, and an essential component of any robust quality management system. Real-time data on airborne particle concentrations, viable microorganism counts, temperature, relative humidity, and differential room pressures provides the evidence base that regulatory inspectors, quality teams, and clinical governance bodies require.

Total Clean Air supplies and integrates environmental monitoring systems tailored to the specific requirements of each healthcare environment. Automated alerting flags any deviation from specification immediately, allowing your team to respond promptly and maintain the comprehensive audit-ready records that MHRA inspections and NHS governance processes demand. Our monitoring solutions can be configured to support the specific data integrity requirements of healthcare quality management systems.

Every healthcare cleanroom project begins with a thorough consultancy phase in which our specialists work closely with your clinical, estates, and quality teams to understand the precise requirements of your facility. We consider the full operational context, including patient flow, staff movement, infection control protocols, and the regulatory framework applicable to your specific activities, before any design work commences.

Our in-house design and engineering teams then develop a solution built precisely around your specification, considering everything from room pressure differentials and ventilation design through to cleanroom furniture, pass-through hatches, and gowning facilities. We ensure that the finished environment supports both clinical compliance and day-to-day operational efficiency.

Once construction is complete, our commissioning and validation team takes the facility through a structured qualification process, producing the comprehensive documentation packages required by the MHRA, NHS governance bodies, and your internal quality management system. Total Clean Air continues to support healthcare clients throughout the operational life of their cleanrooms, providing scheduled maintenance, filter replacement, periodic revalidation, and responsive technical support.